Se sidan i fullversion.

bellasmith2017 RSS

Profilbild
Eftersom bellasmith2017 inte orkat med att skriva något om sig själv, passar vi på att visa några underbara annonser här istället:

what is adc

vimeo.com - 24 aug 2018 av bellasmith2017 i what is adc

What is ADC? Three major components define an ADC—the monoclonal antibody, a cytotoxic payload, and a molecular linker that covalently bridges the other two components. A... Läs mer »

1 Pusha

payload

vimeo.com - 24 aug 2018 av bellasmith2017 i payload

Antibody-drug conjugates (ADCs) are next-generation targeted anti-tumor agents that are constructed by the covalent coupling of a monoclonal antibody with a cytotoxic pay... Läs mer »

1 Pusha

mmae from Creative Biolabs

vimeo.com - 24 aug 2018 av bellasmith2017 i mmae

Binding of mmae, an Auristatin derivative, to the ? and ? tubulin subunits solved by co-crystallography. The interaction between MMAE and aromatic amino acid side chains ... Läs mer »

1 Pusha

conjugate dar

vimeo.com - 24 aug 2018 av bellasmith2017 i httpswwwcreative-bio

To retain antibody bioactivity, mild, near-physiological conditions are often used for conjugate dar reactions. Under these conditions, endogenous amino acids such as Lys... Läs mer »

2 Pusha

cd19 car t cells

vimeo.com - 22 aug 2018 av bellasmith2017 i cd19 car t cells

CD19 is a B cell surface protein expressed throughout B cell development. It is expressed on nearly all B cell malignancies including acute lymphoblastic leukemia (ALL), ... Läs mer »

1 Pusha

car t validation

giphy.com - 22 aug 2018 av bellasmith2017 i car t validation

At Creative Biolabs, our scientists will professionally perform multiple car t validation experiments on the post-transfection CAR-T cells to verify the solid success of ... Läs mer »

1 Pusha

car t cell biomarker

screencast.com - 22 aug 2018 av bellasmith2017 i car t cell biomarker

CAR T cell biomarker provides the most prominent signal of cancer cells for distinguishing from normal cells and the most effective target for immune recognition and dest... Läs mer »

1 Pusha

car design development

vimeo.com - 22 aug 2018 av bellasmith2017 i car design developme

In detail, CAR stands for chimeric antigen receptor or artificial T cell receptor, which is engineered elaborately and endowing an immune effector cell (T cell) with an a... Läs mer »

1 Pusha

dar conjugated

d1087hedyh252c.cloudfront.net - 17 aug 2018 av bellasmith2017 i dar

Creative Biolabs has over a decade of working experience in antibody design and modification to fit various bio-conjugation strategies, especially for the development of ... Läs mer »

1 Pusha

dar conjugate

d1087hedyh252c.cloudfront.net - 17 aug 2018 av bellasmith2017 i dar

One downside in using the endogenous amino acids for ADC development is a heavily dispersed drug-to-antibody ratio (DAR) caused by the non-uniform distribution of the con... Läs mer »

1 Pusha

conjugation site

d1087hedyh252c.cloudfront.net - 17 aug 2018 av bellasmith2017 i conjugation site

Alongside the efforts of antibody engineering, we apply several enzymatic or physical approaches to afford site-specific antibody-drug conjugations by modifying the carbo... Läs mer »

1 Pusha

conjugation dar

d1087hedyh252c.cloudfront.net - 17 aug 2018 av bellasmith2017 i conjugation dar

Denna länk rekommenderas inte av Pushas användare

To achieve a narrower DAR, Creative Biolabs has explored and adopted a variety of methodologies in antibody design and engineering to introduce a series of specific and c... Läs mer »

3 Pusha

antibody design

d1087hedyh252c.cloudfront.net - 17 aug 2018 av bellasmith2017 i antibody design

To achieve more precisely controlled site-directed conjugations and subsequently a narrower distribution of drug-to-antibody ratio (DAR), special moieties with unique con... Läs mer »

2 Pusha

antibody conjugation

d1087hedyh252c.cloudfront.net - 17 aug 2018 av bellasmith2017 i antibody

Scientists at Creative Biolabs are experienced in performing Lysine conjugation (amine reaction) as well as Cysteine conjugation (thiol reactions) to create ADCs using th... Läs mer »

2 Pusha

antibody conjugates

d1087hedyh252c.cloudfront.net - 17 aug 2018 av bellasmith2017 i antibody

As one major component of an antibody-drug conjugate (ADC), the antibody is the key for target specificity and serves as the cargo to deliver the cytotoxic drug (payload)... Läs mer »

1 Pusha

  • Blev medlem: 27 november 2017
  • Senast aktiv: 24 aug 2018
  • Placering på topplistan: 638

Andel populära

13%

Pushar andras

0%

Post-aktivitet

33%